Earth Elixir vs Codeage: Urolithin A Blend Comparison

Reviewed by SOMA HEALTH's Medical Research Team

Earth Elixir and Codeage both build their formulas around urolithin A, then layer in extra actives aimed at cellular aging. If you are deciding between two blends, the useful questions are simple: how much urolithin A do you actually get, what else is in the capsule, and does the added complexity earn its place. Here is an honest, side-by-side look, plus where a straightforward gummy fits.

A quick disclosure before we start: SOMA HEALTH makes a urolithin A gummy, so we are a competitor to both brands discussed here. We have tried to keep this comparison factual and to describe what each product actually is, not to talk you into anything. Ingredient panels and prices change, so always confirm the current label before you buy.

What both products have in common

Urolithin A is not something you eat directly. It is a gut postbiotic: your microbiome converts ellagitannins from foods like pomegranate, walnuts and berries into urolithin A. The catch is that only some people carry the bacteria to make it, and even then usually in small amounts. That variability is the whole reason direct urolithin A supplements exist, and it is the shared premise behind Earth Elixir, Codeage and SOMA HEALTH alike.

The mechanism people care about is mitophagy: the cellular housekeeping process that identifies worn-out mitochondria and recycles them so fresher, better-functioning ones can take their place. Mitochondria are the parts of the cell that turn food and oxygen into usable energy, and their efficiency tends to drift downward with age. Urolithin A has been studied as a way to support that clean-up process. For a fuller primer, our urolithin A guide walks through the biology and the human trial record in plain language, and what is mitophagy covers the recycling step in more depth.

Earth Elixir: urolithin A paired with NAD support

Earth Elixir sells a capsule marketed as a urolithin A and NAD supplement, listing 500 mg of urolithin A alongside nicotinamide riboside, a precursor the body uses to make NAD+. The pitch combines two popular longevity ideas in one capsule: recycle mitochondria with urolithin A, and support cellular NAD+ levels with the riboside. It is typically sold in a 90-capsule bottle with organic positioning. Prices and exact serving sizes shift, so check the current label for the per-serving urolithin A amount and how many capsules make up a daily dose.

The reasonable question is whether the NAD angle is doing what the marketing implies. Nicotinamide riboside is a separate compound with its own, still-developing research base; it is not urolithin A and the two are not interchangeable. Bundling them means you are trusting a single capsule to deliver a meaningful amount of each. If your interest is specifically urolithin A and mitophagy, a combination product makes it harder to know which ingredient, if any, is responsible for how you feel.

Codeage: a liposomal urolithin A stack

Codeage sells a Liposomal Urolithin A capsule listing 500 mg of urolithin A per serving, combined with trans-resveratrol, betaine, CoQ10 and additional ellagitannins, delivered in a liposomal format and sold in a 60-capsule bottle. It is the more elaborate of the two blends, wrapping the core ingredient in a longevity stack. As with Earth Elixir, confirm the label for the current dose, serving size and price rather than relying on any figure quoted online.

Liposomal delivery is a genuine formulation approach, but it is worth being clear-eyed: a liposomal claim on a label is not the same as a published human study showing better urolithin A absorption for that specific product. The added actives, resveratrol and CoQ10 in particular, each have their own separate literature and their own dosing questions. A four-way stack can be appealing if you want several compounds in one capsule, but it also spreads the formula thin and makes it hard to isolate what any single ingredient contributes.

What the human evidence actually supports

Because both blends anchor on urolithin A, the honest comparison starts with what has been shown in people for that ingredient specifically.

Proven in humans

The first-in-human work, Andreux and colleagues in Nature Metabolism (2019), found urolithin A was safe and well tolerated at single doses up to 1,000 mg per day and moved a mitochondrial gene-expression signature in the expected direction. A 2022 randomized trial in older adults by Liu, D'Amico and colleagues (JAMA Network Open) reported improvements in muscle endurance over roughly four months. Singh and colleagues (Cell Reports Medicine, 2022) tested 500 mg and 1,000 mg arms in middle-aged adults over four months and saw benefits in muscle strength and exercise performance.

Newer human research

An eight-week randomized trial in resistance-trained men (Journal of the International Society of Sports Nutrition, 2024) and a 2025 trial in distance runners have extended the work into fitter, more active populations. A 2025 randomized trial published in Nature Aging reported support for immune-cell mitochondrial health in midlife adults over about 28 days, touching on what researchers call inflammaging. A 2024 systematic review in Ageing Research Reviews sums up the state of play fairly: the human evidence is promising but still emerging. You can read the trial-by-trial breakdown in our urolithin A clinical studies summary.

Preclinical, and clearly labeled as such

Much of the excitement traces back to animal and cell work. Ryu and colleagues (Nature Medicine, 2016) showed urolithin A triggered mitophagy, extended lifespan in the worm C. elegans and improved muscle measures in rodents. D'Amico and colleagues (Aging Cell, 2022) explored joint and cartilage outcomes in osteoarthritis models. Areas like skin, gut, brain and heart remain early, preclinical research that is still being explored. These findings are interesting context, but they are not the same as proof in humans, and no blend, however elaborate, changes that.

A key point for this comparison: the strongest human urolithin A data sits at 500 to 1,000 mg per day, with 1,000 mg as the top studied dose. When a product folds urolithin A into a multi-ingredient stack, ask whether the per-serving urolithin A still lands in that studied range, or whether the other actives have crowded it down. Our urolithin A dosage page covers this in detail.

Blend versus single ingredient: how to decide

There is no universally right answer, only trade-offs. A blend like Codeage or Earth Elixir gives you several compounds in one purchase, which some people value for convenience. The downside is that you cannot easily tell which ingredient is responsible for anything you notice, the urolithin A dose may be lower than the studied range once other actives take up space, and you are paying for compounds you may not have researched individually.

A single-ingredient product does the opposite. You know exactly how much urolithin A you are taking, you can match it to the human trial doses, and if you decide to add resveratrol or a NAD precursor later, you control each one separately. Format matters too: both brands here are capsules, while SOMA HEALTH uses a gummy, which some people find easier to take consistently. Consistency, more than any single dose, is what the human trials were built on, they ran for months, not days. If you are curious how gummies stack up across the category, see our roundup of the best urolithin A gummies.

Shop SOMA HEALTH Urolithin A Gummies

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This guide is educational and is not a substitute for advice from a qualified healthcare provider.